Brian Guth : rechercher sur Z-Library

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1

Does Religion Still Matter? Religion and Public Attitudes toward Integration in Europe

Nelsen, Brent F., Guth, James L., Highsmith, Brian

Journal:

Politics and Religion

Année:

2011

Langue:

english

Fichier:

PDF, 134 KB

english, 2011

2

An integrated platform for simultaneous multi-well field potential recording and Fura-2-based calcium transient ratiometry in human induced pluripotent stem cell (hiPSC)-derived cardiomyocytes

Rast, Georg, Weber, Jürgen, Disch, Christoph, Schuck, Elmar, Ittrich, Carina, Guth, Brian D.

Journal:

Journal of Pharmacological and Toxicological Methods

Année:

2015

Langue:

english

Fichier:

PDF, 1.20 MB

english, 2015

3

Successful implantation of an abdominal aortic blood pressure transducer and radio-telemetry transmitter in guinea pigs — Anaesthesia, analgesic management and surgical methods, and their influence on hemodynamic parameters and body temperature

Schmitz, Sabrina, Henke, Julia, Tacke, Sabine, Guth, Brian

Journal:

Journal of Pharmacological and Toxicological Methods

Année:

2016

Langue:

english

Fichier:

PDF, 1.92 MB

english, 2016

4

The evaluation of endpoint variability and implications for study statistical power and sample size in conscious instrumented dogs

Chiang, Alan Y., Guth, Brian D., Pugsley, Michael K., Foley, C. Michael, Doyle, Jennifer M., Engwall, Michael J., Koerner, John E., Parish, Stanley T., Dustan Sarazan, R.

Journal:

Journal of Pharmacological and Toxicological Methods

Année:

2018

Langue:

english

Fichier:

PDF, 833 KB

english, 2018

5

General pharmacology studies in the pharmaceutical industry: Example of a basic program

Michel Pairet, Willi Diederen, Brian Guth, Kozo Kanai, Annerose Mauz, Michael Pieper, Joanne van Ryn, Hans Schierok, Alexander Walland, Ray Winquist

Journal:

Drug Development Research

Année:

1997

Langue:

english

Fichier:

PDF, 109 KB

english, 1997

6

Myocardial creatine kinase exchange rates and 31P NMR relaxation rates in intact pigs

Joel F. Martin, Brian D. Guth, Richard H. Griffey, David E. Hoekenga

Journal:

Magnetic Resonance in Medicine

Année:

1989

Langue:

english

Fichier:

PDF, 547 KB

english, 1989

7

3,5-Dihydro-imidazo[4,5-d]pyridazin-4-ones: A class of potent DPP-4 inhibitors

Matthias Eckhardt, Norbert Hauel, Frank Himmelsbach, Elke Langkopf, Herbert Nar, Michael Mark, Moh Tadayyon, Leo Thomas, Brian Guth, Ralf Lotz

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2008

Langue:

english

Fichier:

PDF, 196 KB

english, 2008

8

Effects of the specific bradycardic agent zatebradine on hemodynamic variables and myocardial blood flow during the early postresuscitation phase in pigs

Hans-Ulrich Strohmenger, Volker Wenzel, Ralf Eberhard, Brian D Guth, Keith G Lurie, Karl H Lindner

Journal:

Année:

1999

Langue:

english

Fichier:

PDF, 103 KB

english, 1999

9

Reduction of exercise-induced regional contractile dysfunction in dogs using a novel calcium channel blocker (Ro 40-5967)

Journal:

Cardiovascular Drugs and Therapy

Année:

1992

Langue:

english

Fichier:

PDF, 509 KB

english, 1992

10

Pressure-flow characteristics in the right and left ventricular perfusion territories of the right coronary artery in swine

Brian D. Guth, Rainer Schulz, Gerd Heusch

Journal:

Pflügers Archiv European Journal of Physiology

Année:

1991

Langue:

english

Fichier:

PDF, 814 KB

english, 1991

11

Interventricular redistribution of myocardial blood flow during metabolic vasodilation

Brian D. Guth, Rainer Schulz, Erik Thaulow

Journal:

Pflügers Archiv European Journal of Physiology

Année:

1991

Langue:

english

Fichier:

PDF, 1.11 MB

english, 1991

12

Pharmacological mechanisms to attenuate sympathetically induced myocardial ischemia

Rainer Schulz, Brian D. Guth, Gerd Heusch

Journal:

Cardiovascular Drugs and Therapy

Année:

1989

Langue:

english

Fichier:

PDF, 1.05 MB

english, 1989

13

Role of calcium channel blockers in experimental exercise-induced ischemia

Erik Thaulow, Brian D. Guth, John Ross

Journal:

Cardiovascular Drugs and Therapy

Année:

1988

Langue:

english

Fichier:

PDF, 1.14 MB

english, 1988

14

Pharmacokinetics and pharmacodynamics of terbogrel, a combined thromboxane A2 receptor and synthase inhibitor, in healthy subjects

Brian D. Guth, Hans Narjes, Hans-Dieter Schubert, Paul Tanswell, Axel Riedel, Gerhard Nehmiz

Journal:

British Journal of Clinical Pharmacology

Année:

2004

Langue:

english

Fichier:

PDF, 290 KB

english, 2004

15

Nonviral monocyte chemoattractant protein-1 gene transfer improves arteriogenesis after femoral artery occlusion

Muhs, A, Lenter, M C, Seidler, R W, Zweigerdt, R, Kirchengast, M, Weser, R, Ruediger, M, Guth, Brian

Journal:

Année:

2004

Langue:

english

Fichier:

PDF, 325 KB

english, 2004

16

8-(3-(R)-Aminopiperidin-1-yl)-7-but-2-ynyl-3-methyl-1-(4-methyl-quinazolin-2-ylmethyl)-3,7-dihydropurine-2,6-dione (BI 1356), a Highly Potent, Selective, Long-Acting, and Orally Bioavailable DPP-4 Inhibitor for the Treatment of Type 2 Diabetes†

Eckhardt, Matthias, Langkopf, Elke, Mark, Michael, Tadayyon, Moh, Thomas, Leo, Nar, Herbert, Pfrengle, Waldemar, Guth, Brian, Lotz, Ralf, Sieger, Peter

Journal:

Journal of Medicinal Chemistry

Année:

2007

Langue:

english

Fichier:

PDF, 235 KB

english, 2007

17

Minimal α1- and α2-adrenoceptor-mediated coronary vasoconstriction in the anaesthetized swine

Rainer Schulz, Ron J. Oudiz, Brian D. Guth, Gerd Heusch

Journal:

Naunyn-Schmiedeberg's Archives of Pharmacology

Année:

1990

Langue:

english

Fichier:

PDF, 899 KB

english, 1990

18

Risk Factors and Outcomes of Surgical Site Infection in Children

Brian T. Bucher, Rebecca M. Guth, Alexis M. Elward, Nicholas A. Hamilton, Patrick A. Dillon, Brad W. Warner, Martin S. Keller

Journal:

Journal of the American College of Surgeons

Année:

2011

Langue:

english

Fichier:

PDF, 200 KB

english, 2011

19

Developing a strategy for the nonclinical assessment of proarrhythmic risk of pharmaceuticals due to prolonged ventricular repolarization

Brian D Guth, Sabine Germeyer, Willi Kolb, Michael Markert

Journal:

Journal of Pharmacological and Toxicological Methods

Année:

2004

Langue:

english

Fichier:

PDF, 582 KB

english, 2004

20

A novel propellant-free inhalation drug delivery system for cardiovascular drug safety evaluation in conscious dogs

Michael Markert, Anja Klumpp, Thomas Trautmann, Brian Guth

Journal:

Journal of Pharmacological and Toxicological Methods

Année:

2004

Langue:

english

Fichier:

PDF, 980 KB

english, 2004

21

Optimizing the experimental environment for dog telemetry studies

Anja Klumpp, Thomas Trautmann, Michael Markert, Brian Guth

Journal:

Journal of Pharmacological and Toxicological Methods

Année:

2006

Langue:

english

Fichier:

PDF, 501 KB

english, 2006

22

Effect of commonly used vehicles on gastrointestinal, renal, and liver function in rats

Sabine Pestel, Hans-Juergen Martin, Gerd-Michael Maier, Brian Guth

Journal:

Journal of Pharmacological and Toxicological Methods

Année:

2006

Langue:

english

Fichier:

PDF, 404 KB

english, 2006

23

THE VALUE ADDED BY MEASURING MYOCARDIAL CONTRACTILITY IN SAFETY PHARMACOLOGICAL PROFILING OF DRUG CANDIDATES

Anja Klumpp, Thomas Trautmann, Michael Markert, Brian Guth

Journal:

Journal of Pharmacological and Toxicological Methods

Année:

2007

Langue:

english

Fichier:

PDF, 65 KB

english, 2007

24

Evaluation of cardiovascular and ECG parameters in the normal, freely moving Göttingen Minipig

Miriam Stubhan, Michael Markert, Karin Mayer, Thomas Trautmann, Anja Klumpp, Brian Guth

Journal:

Journal of Pharmacological and Toxicological Methods

Année:

2008

Langue:

english

Fichier:

PDF, 57 KB

english, 2008

25

The value added by measuring myocardial contractility ‘in vivo’ in safety pharmacological profiling of drug candidates

Michael Markert, Anja Klumpp, Thomas Trautmann, Karin Mayer, Miriam Stubhan, Brian Guth

Journal:

Journal of Pharmacological and Toxicological Methods

Année:

2007

Langue:

english

Fichier:

PDF, 1.01 MB

english, 2007

26

Evaluation of cardiovascular and ECG parameters in the normal, freely moving Göttingen Minipig

Miriam Stubhan, Michael Markert, Karin Mayer, Thomas Trautmann, Anja Klumpp, Julia Henke, Brian Guth

Journal:

Journal of Pharmacological and Toxicological Methods

Année:

2008

Langue:

english

Fichier:

PDF, 1.55 MB

english, 2008

27

Heart rate correction models to detect QT interval prolongation in novel pharmaceutical development

Michael Markert, Ruijun Shen, Thomas Trautmann, Brian Guth

Journal:

Journal of Pharmacological and Toxicological Methods

Année:

2008

Langue:

english

Fichier:

PDF, 70 KB

english, 2008

28

Validation of the normal, freely moving Göttingen minipig for pharmacological safety testing

Michael Markert, Miriam Stubhan, Karin Mayer, Thomas Trautmann, Anja Klumpp, Annette Schuler-Metz, Kurt Schumacher, Brian Guth

Journal:

Journal of Pharmacological and Toxicological Methods

Année:

2009

Langue:

english

Fichier:

PDF, 1.73 MB

english, 2009

29

The impact of body temperature on the QT (QTc) in conscious dogs

Karin Mayer, Anja Klumpp, Thomas Trautmann, Michael Markert, Kurt Schumacher, Brian Guth

Journal:

Journal of Pharmacological and Toxicological Methods

Année:

2009

Langue:

english

Fichier:

PDF, 52 KB

english, 2009

30

Recording of IKS current in the whole cell patch clamp—How to counteract the run down phenomenon

Maike Knaeple, Brian Guth, Georg Rast

Journal:

Journal of Pharmacological and Toxicological Methods

Année:

2010

Langue:

english

Fichier:

PDF, 64 KB

english, 2010

31

Assessment of sensitivity of three ECG recording methods used in dog toxicology and safety pharmacology studies

Pierre Laine, Mark Deurink, Alan Bass, Jonathan Bright, Richard Briscoe, Simon Chivers, Brian Guth, Michael Markert, Peter Siegl, Jean-Pierre Valentin

Journal:

Journal of Pharmacological and Toxicological Methods

Année:

2010

Langue:

english

Fichier:

PDF, 48 KB

english, 2010

32

Evaluation of a new GI-telemetry system for dogs

Thomas Trautmann, Michael Markert, Anja Klumpp, Karin Mayer, Brian Guth, Thomas Trautmann

Journal:

Journal of Pharmacological and Toxicological Methods

Année:

2011

Langue:

english

Fichier:

PDF, 65 KB

english, 2011

33

Evaluation of an automated arrhythmia detection software

Michael Markert, Thomas Trautmann, Florence Koeppel, David Labarre, Brian Guth

Journal:

Journal of Pharmacological and Toxicological Methods

Année:

2011

Langue:

english

Fichier:

PDF, 55 KB

english, 2011

34

Heart rate correction models to detect QT interval prolongation in novel pharmaceutical development

Michael Markert, Ruijun Shen, Thomas Trautmann, Brian Guth

Journal:

Journal of Pharmacological and Toxicological Methods

Année:

2011

Langue:

english

Fichier:

PDF, 2.84 MB

english, 2011

35

Continuous assessment of multiple vital physiological functions in conscious freely moving rats using telemetry and a plethysmography system

Hans Schierok, Michael Markert, Michel Pairet, Brian Guth

Journal:

Journal of Pharmacological and Toxicological Methods

Année:

2000

Langue:

english

Fichier:

PDF, 561 KB

english, 2000

36

Decreased systolic wall thickening in myocardium adjacent to ischemic zones in conscious swine during brief coronary artery occlusion

Brian D. Guth, Francis C. White, Kim P. Gallagher, Colin M. Bloor

Journal:

American Heart Journal

Année:

1984

Langue:

english

Fichier:

PDF, 1.24 MB

english, 1984

37

Detection of ischemic wall dysfunction: Comparison between M-mode echocardiography and sonomicrometry

Brian Guth, Robert Savage, Francis White, Arthur Hagan, Linda Samtoy, Colin Bloor

Journal:

American Heart Journal

Année:

1984

Langue:

english

Fichier:

PDF, 2.78 MB

english, 1984

38

Ischemic myocardial hysfunction assessed by temporal Fourier transform of regional myocardial wall thickening

Gerd Heusch, Brian D. Guth, Thomas Widmann, Kirk L. Peterson, John Ross Jr.

Journal:

American Heart Journal

Année:

1987

Langue:

english

Fichier:

PDF, 2.09 MB

english, 1987

39

Guanidine Derivatives as Combined Thromboxane A 2 Receptor Antagonists and Synthase Inhibitors

Soyka, Rainer, Guth, Brian D., Weisenberger, Hans M., Luger, Peter, Müller, Thomas H.

Journal:

Journal of Medicinal Chemistry

Année:

1999

Langue:

english

Fichier:

PDF, 524 KB

english, 1999

40

Evidence against significant Alpha2 postsynaptic coronary vasoconstruction in resting man

Ciro Indolfi, Federico Piscione, Brian D. Guth, Paolo Golino, Bruno Villari, Amelia Focaocio, Massimo Chiariello

Journal:

Journal of the American College of Cardiology

Année:

1990

Fichier:

PDF, 305 KB

1990

41

Evaluation of digital angiographic of myocardial perfusion in a multiple coronary stenosis model in the pig

Toshiro Miura, Valmik Bhargava, Brian D. Guth, Shunichi Miyasaki, Ciro Indolfi, Girish Hagan, Kirk L. Peterson

Journal:

Journal of the American College of Cardiology

Année:

1990

Fichier:

PDF, 325 KB

1990

42

Evaluation of a method to correct the contractility index LVdP/dtmax for changes in heart rate

Michael Markert, Thomas Trautmann, Marcus Groß, Anja Ege, Karin Mayer, Brian Guth

Journal:

Journal of Pharmacological and Toxicological Methods

Année:

2012

Langue:

english

Fichier:

PDF, 1.19 MB

english, 2012

43

Evaluation of a LVdP/dt rate-correction method

Thomas Trautmann, Marcus Groß, Anja Ege, Karin Mayer, Michael Markert, Brian Guth

Journal:

Journal of Pharmacological and Toxicological Methods

Année:

2012

Langue:

english

Fichier:

PDF, 57 KB

english, 2012

44

Gastric secretion in the rat: Influence of analgesics

Astrid Jaehnige, Stefanie Hoell, Iris Erni, Silke Schlager-Schaelkle, Brian Guth, Sabine Pestel

Journal:

Journal of Pharmacological and Toxicological Methods

Année:

2012

Langue:

english

Fichier:

PDF, 53 KB

english, 2012

45

Experimental exercise-induced ischemia: Drug therapy can eliminate regional dysfunction and oxygen supply-demand imbalance

Brian D. Guth, Tsukasa Tajimi, Rainald Seitelberger, Jong-Dae Lee, Masunori Matsuzaki, John Ross Jr.

Journal:

Journal of the American College of Cardiology

Année:

1986

Langue:

english

Fichier:

PDF, 1.35 MB

english, 1986

46

Regional myocardial blood flow, function and metabolism using phosphorus-31 nuclear magnetic resonance spectroscopy during ischemia and reperfusion in dogs

Brian D. Guth, Joel F. Martin, Gerd Heusch, John Ross Jr.

Journal:

Journal of the American College of Cardiology

Année:

1987

Langue:

english

Fichier:

PDF, 1.10 MB

english, 1987

47

Role of asynchrony on regional left ventricular diastolic function in exercising dogs with ischemia

Shuniehi Miyazaki, Brian D. Guth, Toshiro Miura, Ciro Indolfi, John Ross Jr.

Journal:

Journal of the American College of Cardiology

Année:

1991

Langue:

english

Fichier:

PDF, 180 KB

english, 1991

48

Cardiovascular safety pharmacology (including QT interval)

Journal:

Toxicology Letters

Année:

2009

Langue:

english

Fichier:

PDF, 42 KB

english, 2009

49

Amino acid content of guinea pig perilymph collected under conditions of quiet or sound stimulation

Melamed, Brian, Norris, Charles, Bryant, Georgia, Guth, Paul

Journal:

Hearing Research

Année:

1982

Langue:

english

Fichier:

PDF, 396 KB

english, 1982

50

Effect of CC-chemokines (MCP-1) in a novel porcine model of peripheral vascular disease

Voskuil, Michiel, Van Royen, Niels, Hoefer, Imo, Guth, Brian, Seidler, Randolph, Scheffler, Klaus, Grundmann, Sebastian, Hennig, Juergen, Schaper, Wolfgang, Bode, Christoph, Piek, Jan J., Buschmann, I

Journal:

Journal of the American College of Cardiology

Année:

2003

Langue:

english

Fichier:

PDF, 193 KB

english, 2003